Preclinical activity of selinexor, an inhibitor of XPO1, in sarcoma. [electronic resource]
Producer: 20171127Description: 16581-92 p. digitalISSN:- 1949-2553
- Animals
- Apoptosis -- drug effects
- Blotting, Western
- Cell Line, Tumor
- Cell Survival -- drug effects
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor -- methods
- Female
- G1 Phase Cell Cycle Checkpoints -- drug effects
- Humans
- Hydrazines -- pharmacology
- Karyopherins -- antagonists & inhibitors
- Mice, Nude
- Proto-Oncogene Proteins c-kit -- genetics
- Receptors, Cytoplasmic and Nuclear -- antagonists & inhibitors
- Reverse Transcriptase Polymerase Chain Reaction
- Sarcoma -- drug therapy
- Signal Transduction -- drug effects
- Triazoles -- pharmacology
- Xenograft Model Antitumor Assays -- methods
- Exportin 1 Protein
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Publication Type: Journal Article
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