Genes encoding members of the JAK-STAT pathway or epigenetic regulators are recurrently mutated in T-cell prolymphocytic leukaemia. [electronic resource]
Producer: 20160822Description: 265-73 p. digitalISSN:- 1365-2141
- Aged
- Biomarkers, Tumor -- genetics
- Cohort Studies
- DNA Mutational Analysis -- methods
- Epigenesis, Genetic -- genetics
- Female
- Genetic Markers -- genetics
- Humans
- Janus Kinase 3 -- genetics
- Leukemia, Prolymphocytic, T-Cell -- genetics
- Male
- Middle Aged
- Mutation -- genetics
- Proto-Oncogene Proteins -- genetics
- Recurrence
- Repressor Proteins -- genetics
- STAT5 Transcription Factor -- genetics
- Signal Transduction
- rhoA GTP-Binding Protein -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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