Donepezil loaded PLGA-b-PEG nanoparticles: their ability to induce destabilization of amyloid fibrils and to cross blood brain barrier in vitro. [electronic resource]
Producer: 20180227Description: 33-45 p. digitalISSN:- 1435-1463
- Amyloid -- drug effects
- Amyloid beta-Peptides -- metabolism
- Astrocytes -- drug effects
- Blood-Brain Barrier -- drug effects
- Capillary Permeability -- drug effects
- Cell Line
- Cholinesterase Inhibitors -- administration & dosage
- Donepezil
- Dose-Response Relationship, Drug
- Drug Carriers
- Endothelial Cells -- drug effects
- Gene Expression -- drug effects
- Humans
- Indans -- administration & dosage
- Nanoparticles -- ultrastructure
- Neuroprotective Agents -- administration & dosage
- Peptide Fragments -- metabolism
- Piperidines -- administration & dosage
- Polyethylene Glycols
- Polyglactin 910
- Protein Stability -- drug effects
- Rifampin -- pharmacology
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Publication Type: Journal Article
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