Acquisition of a CD19-negative myeloid phenotype allows immune escape of MLL-rearranged B-ALL from CD19 CAR-T-cell therapy. [electronic resource]
Producer: 20170627Description: 2406-10 p. digitalISSN:- 1528-0020
- Antigens, CD19 -- genetics
- Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
- Bone Marrow -- pathology
- Chromosomes, Human, Pair 11 -- genetics
- Clone Cells
- Combined Modality Therapy
- Female
- Histone-Lysine N-Methyltransferase -- genetics
- Humans
- Immunophenotyping
- Immunotherapy, Adoptive
- Infant
- Leukemia, Myeloid, Acute -- genetics
- Lymphocyte Depletion
- Middle Aged
- Myeloid-Lymphoid Leukemia Protein -- genetics
- Neoplastic Stem Cells
- Oncogene Proteins, Fusion -- genetics
- Precursor B-Cell Lymphoblastic Leukemia-Lymphoma -- genetics
- Receptors, Antigen, T-Cell -- immunology
- Recurrence
- Remission Induction
- Salvage Therapy
- T-Lymphocyte Subsets -- immunology
- Translocation, Genetic
- Tumor Escape
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Publication Type: Case Reports; Journal Article
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