Cucurbitacin B inhibits the stemness and metastatic abilities of NSCLC via downregulation of canonical Wnt/β-catenin signaling axis. [electronic resource]
Producer: 20161220Description: 21860 p. digitalISSN:- 2045-2322
- A549 Cells
- Animals
- Blotting, Western
- Carcinoma, Non-Small-Cell Lung -- chemically induced
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Cell Transformation, Neoplastic -- drug effects
- Down-Regulation -- drug effects
- Epithelial-Mesenchymal Transition -- drug effects
- Female
- Human Umbilical Vein Endothelial Cells
- Humans
- Immunoprecipitation
- Lung Neoplasms -- chemically induced
- Mice
- Microscopy, Fluorescence
- Neovascularization, Physiologic -- drug effects
- Nitrosamines -- toxicity
- RNA Interference
- RNA, Small Interfering -- metabolism
- Transforming Growth Factor beta1 -- pharmacology
- Triterpenes -- toxicity
- Wnt Signaling Pathway -- drug effects
- Wnt3 Protein -- antagonists & inhibitors
- Wnt3A Protein -- antagonists & inhibitors
- beta Catenin -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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