Integrated genomic approaches identify upregulation of SCRN1 as a novel mechanism associated with acquired resistance to erlotinib in PC9 cells harboring oncogenic EGFR mutation. [electronic resource]
Producer: 20171218Description: 13797-809 p. digitalISSN:- 1949-2553
- Animals
- Apoptosis
- Biomarkers, Tumor -- genetics
- Carcinogenesis
- Carcinoma, Non-Small-Cell Lung -- drug therapy
- Cell Proliferation
- Drug Resistance, Neoplasm -- genetics
- ErbB Receptors -- antagonists & inhibitors
- Erlotinib Hydrochloride -- pharmacology
- Genomics -- methods
- Humans
- Lung Neoplasms -- drug therapy
- Male
- Mice
- Mice, Nude
- Mutation
- Nerve Tissue Proteins -- genetics
- Protein Kinase Inhibitors -- pharmacology
- RNA, Small Interfering -- genetics
- Signal Transduction
- Tumor Cells, Cultured
- Xenograft Model Antitumor Assays
No physical items for this record
Publication Type: Journal Article
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