Lovastatin protects keratinocytes from DNA damage-related pro-apoptotic stress responses stimulated by anticancer therapeutics. [electronic resource]
Producer: 20160719Description: 1082-92 p. digitalISSN:- 0006-3002
- Adult
- Antibiotics, Antineoplastic -- pharmacology
- Apoptosis -- drug effects
- Ataxia Telangiectasia Mutated Proteins -- metabolism
- Blotting, Western
- Cell Cycle -- drug effects
- Cell Survival -- drug effects
- Cells, Cultured
- Checkpoint Kinase 1
- DNA Damage -- drug effects
- Dose-Response Relationship, Drug
- Dose-Response Relationship, Radiation
- Doxorubicin -- pharmacology
- Enzyme Activation -- drug effects
- Histones -- metabolism
- Humans
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Keratinocytes -- drug effects
- Lovastatin -- pharmacology
- Protein Kinases -- metabolism
- Radiation, Ionizing
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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