Chronic use of pravastatin reduces insulin exocytosis and increases β-cell death in hypercholesterolemic mice. [electronic resource]
Producer: 20160728Description: 42-52 p. digitalISSN:- 1879-3185
- Animals
- Drug Administration Schedule
- Exocytosis -- drug effects
- Female
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- toxicity
- Hypercholesterolemia -- genetics
- Insulin -- metabolism
- Insulin-Secreting Cells -- drug effects
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Pravastatin -- toxicity
- Receptors, LDL -- deficiency
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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