Asymmetric dimethylarginine (ADMA) elevation and arginase up-regulation contribute to endothelial dysfunction related to insulin resistance in rats and morbidly obese humans. [electronic resource]
Producer: 20170807Description: 3045-60 p. digitalISSN:- 1469-7793
- Adipose Tissue -- drug effects
- Adult
- Aged
- Animals
- Arginase -- antagonists & inhibitors
- Arginine -- analogs & derivatives
- Dose-Response Relationship, Drug
- Endothelium, Vascular -- drug effects
- Enzyme Inhibitors -- pharmacology
- Female
- Humans
- Insulin Resistance -- physiology
- Male
- Middle Aged
- Obesity, Morbid -- metabolism
- Organ Culture Techniques
- Rats
- Rats, Sprague-Dawley
- Up-Regulation -- drug effects
- Vasodilation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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