Lapatinib inhibits CIP2A/PP2A/p-Akt signaling and induces apoptosis in triple negative breast cancer cells. [electronic resource]
Producer: 20161230Description: 9135-49 p. digitalISSN:- 1949-2553
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Autoantigens
- Cell Line, Tumor
- Disease Models, Animal
- ErbB Receptors -- antagonists & inhibitors
- Humans
- Lapatinib
- MCF-7 Cells
- Membrane Proteins -- antagonists & inhibitors
- Mice
- Mice, Nude
- Promoter Regions, Genetic -- drug effects
- Protein Kinase Inhibitors -- pharmacology
- Protein Phosphatase 2 -- antagonists & inhibitors
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Quinazolines -- pharmacology
- Receptor, ErbB-2 -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Triple Negative Breast Neoplasms -- drug therapy
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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