Divergence of Antiangiogenic Activity and Hepatotoxicity of Different Stereoisomers of Itraconazole. [electronic resource]
Producer: 20180122Description: 2709-20 p. digitalISSN:- 1557-3265
- Angiogenesis Inhibitors -- chemistry
- Animals
- Cell Line, Tumor
- Cholesterol -- metabolism
- Coculture Techniques
- Female
- Hepatocytes -- drug effects
- Human Umbilical Vein Endothelial Cells -- drug effects
- Humans
- Inhibitory Concentration 50
- Itraconazole -- chemistry
- Liver -- drug effects
- Male
- Mice, Inbred BALB C
- Mice, Nude
- Middle Aged
- Neovascularization, Physiologic -- drug effects
- Pericytes -- drug effects
- Protein Processing, Post-Translational
- Stereoisomerism
- Vascular Endothelial Growth Factor Receptor-2 -- metabolism
- Xenograft Model Antitumor Assays
- Young Adult
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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