Discovery of a novel anticancer agent with both anti-topoisomerase I and II activities in hepatocellular carcinoma SK-Hep-1 cells in vitro and in vivo: Cinnamomum verum component 2-methoxycinnamaldehyde. [electronic resource]
Producer: 20161011Description: 141-53 p. digitalISSN:- 1177-8881
- Acrolein -- analogs & derivatives
- Animals
- Antineoplastic Agents, Phytogenic -- isolation & purification
- Apoptosis -- drug effects
- Carcinoma, Hepatocellular -- drug therapy
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cinnamomum zeylanicum -- chemistry
- DNA Topoisomerases, Type I -- drug effects
- DNA Topoisomerases, Type II -- drug effects
- Dose-Response Relationship, Drug
- Humans
- Liver Neoplasms -- drug therapy
- Male
- Membrane Potential, Mitochondrial -- drug effects
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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