Kinetic analysis and molecular modeling of the inhibition mechanism of roneparstat (SST0001) on human heparanase. [electronic resource]
Producer: 20171227Description: 640-54 p. digitalISSN:- 1460-2423
- Acidobacteria -- chemistry
- Amino Acid Motifs
- Binding Sites
- Carbohydrate Sequence
- Enzyme Inhibitors -- chemistry
- Fondaparinux
- Glucuronidase -- antagonists & inhibitors
- Heparin -- analogs & derivatives
- Humans
- Kinetics
- Molecular Docking Simulation
- Molecular Dynamics Simulation
- Polysaccharides -- chemistry
- Protein Binding
- Protein Conformation, alpha-Helical
- Protein Conformation, beta-Strand
- Protein Interaction Domains and Motifs
- Recombinant Proteins -- chemistry
- Structural Homology, Protein
- Substrate Specificity
- Thermodynamics
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Publication Type: Journal Article
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