Synphilin-1 attenuates mutant LRRK2-induced neurodegeneration in Parkinson's disease models. [electronic resource]
Producer: 20161213Description: 672-80 p. digitalISSN:- 1460-2083
- Animals
- Animals, Genetically Modified
- Carrier Proteins -- genetics
- Cell Line, Tumor
- Disease Models, Animal
- Dopamine -- metabolism
- Drosophila
- Gene Knockdown Techniques
- HEK293 Cells
- Humans
- Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 -- genetics
- Mice
- Mutation
- Nerve Degeneration -- genetics
- Nerve Tissue Proteins -- genetics
- Neurons -- enzymology
- Parkinson Disease -- enzymology
- Phosphorylation
- Protein Interaction Domains and Motifs
- alpha-Synuclein -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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