Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer. [electronic resource]
Producer: 20160428Description: 413-417 p. digitalISSN:- 1476-4687
- Animals
- Azepines -- pharmacology
- Binding, Competitive -- drug effects
- Casein Kinase II -- metabolism
- Cell Cycle Proteins
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Chromatin -- genetics
- Drug Resistance, Neoplasm -- drug effects
- Epigenesis, Genetic -- drug effects
- Female
- Gene Expression Regulation, Neoplastic -- drug effects
- Genome, Human -- drug effects
- Humans
- Mediator Complex Subunit 1 -- metabolism
- Mice
- Nuclear Proteins -- antagonists & inhibitors
- Phosphorylation -- drug effects
- Phosphoserine -- metabolism
- Protein Binding -- drug effects
- Protein Phosphatase 2 -- metabolism
- Protein Structure, Tertiary -- drug effects
- Proteomics
- Transcription Factors -- antagonists & inhibitors
- Transcription, Genetic -- drug effects
- Triazoles -- pharmacology
- Triple Negative Breast Neoplasms -- drug therapy
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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