HDAC inhibitors suppress c-Jun/Fra-1-mediated proliferation through transcriptionally downregulating MKK7 and Raf1 in neuroblastoma cells. [electronic resource]
Producer: 20170123Description: 6727-47 p. digitalISSN:- 1949-2553
- Animals
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Down-Regulation -- drug effects
- Gene Knockdown Techniques
- Heterografts
- Histone Deacetylase Inhibitors -- pharmacology
- Humans
- JNK Mitogen-Activated Protein Kinases -- genetics
- MAP Kinase Kinase 7 -- genetics
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Neuroblastoma -- genetics
- Protein Multimerization
- Proto-Oncogene Proteins c-fos -- antagonists & inhibitors
- Proto-Oncogene Proteins c-raf -- antagonists & inhibitors
- RNA, Small Interfering -- administration & dosage
- Transcription Factor AP-1 -- metabolism
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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