Inhibition of Hif1α prevents both trauma-induced and genetic heterotopic ossification. [electronic resource]
Producer: 20160613Description: E338-47 p. digitalISSN:- 1091-6490
- Activin Receptors, Type I -- metabolism
- Adipose Tissue -- drug effects
- Animals
- Burns -- complications
- Chondrogenesis -- drug effects
- Disease Models, Animal
- Gene Regulatory Networks -- drug effects
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit -- antagonists & inhibitors
- Integrases -- metabolism
- Luminescent Measurements
- Mesenchymal Stem Cells -- drug effects
- Mice, Knockout
- Models, Biological
- Mustard Compounds -- pharmacology
- Ossification, Heterotopic -- diagnostic imaging
- Phenylpropionates -- pharmacology
- RNA, Messenger -- genetics
- Receptor, Platelet-Derived Growth Factor alpha -- metabolism
- SOX9 Transcription Factor -- metabolism
- Signal Transduction -- drug effects
- Sirolimus -- pharmacology
- Tendons -- drug effects
- Tenotomy
- Up-Regulation -- drug effects
- Wound Healing -- drug effects
- Wounds and Injuries -- complications
- X-Ray Microtomography
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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