Pristimerin demonstrates anticancer potential in colorectal cancer cells by inducing G1 phase arrest and apoptosis and suppressing various pro-survival signaling proteins. [electronic resource]
Producer: 20161017Description: 1091-100 p. digitalISSN:- 1791-2431
- Adenocarcinoma -- pathology
- Antineoplastic Agents, Phytogenic -- pharmacology
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- biosynthesis
- Cell Cycle Proteins -- biosynthesis
- Cell Line, Tumor
- Colorectal Neoplasms -- pathology
- Drug Screening Assays, Antitumor
- G1 Phase -- drug effects
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Intracellular Signaling Peptides and Proteins -- biosynthesis
- Membrane Potential, Mitochondrial -- drug effects
- Neoplasm Proteins -- biosynthesis
- Pentacyclic Triterpenes
- Signal Transduction -- drug effects
- Triterpenes -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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