Simultaneous gene silencing of KRAS and anti-apoptotic genes as a multitarget therapy. [electronic resource]
Producer: 20161101Description: 3984-92 p. digitalISSN:- 1949-2553
- Adaptor Proteins, Signal Transducing -- genetics
- Animals
- Apoptosis
- Blotting, Western
- Cell Proliferation
- Female
- Gene Silencing
- Humans
- Inhibitor of Apoptosis Proteins -- genetics
- Mice
- Myeloid Cell Leukemia Sequence 1 Protein -- genetics
- Pancreatic Neoplasms -- genetics
- Proto-Oncogene Proteins p21(ras) -- antagonists & inhibitors
- RNA, Messenger -- genetics
- RNA, Small Interfering -- genetics
- Real-Time Polymerase Chain Reaction
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction
- Survivin
- Tumor Cells, Cultured
- X-Linked Inhibitor of Apoptosis Protein -- genetics
- Xenograft Model Antitumor Assays
- bcl-X Protein -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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