Sinomenine potentiates P815 cell degranulation via upregulation of Ca2+ mobilization through the Lyn/PLCγ/IP3R pathway. [electronic resource]
Producer: 20170407Description: 676-683 p. digitalISSN:- 2058-7384
- Anaphylaxis -- drug therapy
- Animals
- Anti-Allergic Agents -- pharmacology
- Anti-Inflammatory Agents -- pharmacology
- Calcium -- metabolism
- Cell Degranulation -- drug effects
- Cell Line, Tumor
- Drug Hypersensitivity -- drug therapy
- Inflammation -- drug therapy
- Inositol 1,4,5-Trisphosphate Receptors -- metabolism
- Interleukin-6 -- metabolism
- Male
- Mast Cells -- drug effects
- Mice
- Mice, Inbred BALB C
- Morphinans -- pharmacology
- Phospholipase C gamma -- metabolism
- Phosphorylation -- drug effects
- Signal Transduction -- drug effects
- Up-Regulation -- drug effects
- src-Family Kinases -- metabolism
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Publication Type: Journal Article
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