Intrathecal injection of phosphodiesterase 4B-specific siRNA attenuates neuropathic pain in rats with L5 spinal nerve ligation. [electronic resource]
Producer: 20161031Description: 1914-22 p. digitalISSN:- 1791-3004
- Animals
- CD11b Antigen -- metabolism
- Cyclic Nucleotide Phosphodiesterases, Type 4 -- genetics
- Cytokines -- metabolism
- Enzyme Activation
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Gene Expression Regulation, Enzymologic
- Glial Fibrillary Acidic Protein -- metabolism
- Injections, Spinal
- Ligation
- Lumbar Vertebrae -- drug effects
- Male
- Neuralgia -- metabolism
- Pain Threshold
- Phosphorylation
- RNA, Messenger -- genetics
- RNA, Small Interfering -- administration & dosage
- Rats, Sprague-Dawley
- Spinal Nerves -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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