In silico modelling of prostacyclin and other lipid mediators to nuclear receptors reveal novel thyroid hormone receptor antagonist properties. [electronic resource]
Producer: 20161213Description: 18-27 p. digitalISSN:- 1098-8823
- Animals
- Binding, Competitive -- drug effects
- Computer Simulation
- Dose-Response Relationship, Drug
- Epoprostenol -- analogs & derivatives
- Humans
- Ligands
- Male
- Mesenteric Arteries -- drug effects
- Models, Molecular
- Myography -- methods
- Protein Domains
- Rats, Wistar
- Receptors, Cytoplasmic and Nuclear -- agonists
- Receptors, Thyroid Hormone -- antagonists & inhibitors
- Thiazoles -- chemistry
- Thyroid Hormone Receptors alpha -- antagonists & inhibitors
- Thyroid Hormone Receptors beta -- antagonists & inhibitors
- Triiodothyronine -- metabolism
- Vasodilation -- drug effects
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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