CHCHD10 mutations promote loss of mitochondrial cristae junctions with impaired mitochondrial genome maintenance and inhibition of apoptosis. [electronic resource]
Producer: 20160928Description: 58-72 p. digitalISSN:- 1757-4684
- Alleles
- Apoptosis -- genetics
- Cell Line
- Cytochromes c -- metabolism
- DNA Repair -- drug effects
- DNA, Mitochondrial -- analysis
- Genome, Mitochondrial
- HeLa Cells
- Humans
- Hydrogen Peroxide -- toxicity
- Lysosomes -- metabolism
- Membrane Potential, Mitochondrial
- Mitochondria -- genetics
- Mitochondrial Diseases -- genetics
- Mitochondrial Proteins -- genetics
- Mutation
- Oxidative Stress -- drug effects
- Real-Time Polymerase Chain Reaction
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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