Blocking FGF2 with a new specific monoclonal antibody impairs angiogenesis and experimental metastatic melanoma, suggesting a potential role in adjuvant settings. [electronic resource]
Producer: 20160614Description: 151-60 p. digitalISSN:- 1872-7980
- Angiogenesis Inhibitors -- metabolism
- Animals
- Antibodies, Monoclonal -- metabolism
- Antigens, CD34 -- metabolism
- Cell Line, Tumor
- Fibroblast Growth Factor 2 -- antagonists & inhibitors
- Human Umbilical Vein Endothelial Cells -- drug effects
- Immunohistochemistry
- Lung Neoplasms -- blood supply
- Male
- Melanoma, Experimental -- blood supply
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Molecular Targeted Therapy
- Neovascularization, Pathologic
- Neovascularization, Physiologic -- drug effects
- Signal Transduction -- drug effects
- Time Factors
- Tomography, Emission-Computed, Single-Photon
- Tomography, X-Ray Computed
- Tumor Burden
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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