Resveratrol overcomes gefitinib resistance by increasing the intracellular gefitinib concentration and triggering apoptosis, autophagy and senescence in PC9/G NSCLC cells. [electronic resource]
Producer: 20161006Description: 17730 p. digitalISSN:- 2045-2322
- ATP Binding Cassette Transporter, Subfamily G, Member 2
- ATP-Binding Cassette Transporters -- biosynthesis
- Apoptosis -- drug effects
- Autophagy -- drug effects
- Carcinoma, Non-Small-Cell Lung -- drug therapy
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cellular Senescence -- drug effects
- Cytochrome P-450 CYP1A1 -- biosynthesis
- Drug Resistance, Neoplasm -- drug effects
- Drug Synergism
- Gefitinib
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Neoplasm Proteins -- biosynthesis
- Quinazolines -- administration & dosage
- Resveratrol
- Stilbenes -- administration & dosage
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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