Antibiotic drug tigecycline inhibits melanoma progression and metastasis in a p21CIP1/Waf1-dependent manner. [electronic resource]
Producer: 20161213Description: 3171-85 p. digitalISSN:- 1949-2553
- Animals
- Antineoplastic Agents -- pharmacology
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Cyclin E -- biosynthesis
- Cyclin-Dependent Kinase 2 -- biosynthesis
- Cyclin-Dependent Kinase Inhibitor p21 -- metabolism
- Disease Progression
- Down-Regulation -- drug effects
- Epithelial-Mesenchymal Transition -- drug effects
- Female
- G1 Phase Cell Cycle Checkpoints -- drug effects
- Humans
- Melanoma -- drug therapy
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Minocycline -- analogs & derivatives
- Neoplasm Invasiveness -- prevention & control
- Neoplasm Metastasis -- drug therapy
- Oncogene Proteins -- biosynthesis
- Skin Neoplasms
- Tigecycline
- Xenograft Model Antitumor Assays
- Melanoma, Cutaneous Malignant
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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