Dose-dependent DNA adduct formation by cinnamaldehyde and other food-borne α,β-unsaturated aldehydes predicted by physiologically based in silico modelling. [electronic resource]
Producer: 20161011Description: 114-25 p. digitalISSN:- 1879-3177
- Alcohol Dehydrogenase -- metabolism
- Aldehyde Dehydrogenase -- metabolism
- Aldehyde Reductase -- metabolism
- Aldehydes -- toxicity
- Animals
- Computer Simulation
- DNA Adducts
- Diet
- Female
- Flavoring Agents -- toxicity
- Glutathione -- metabolism
- Glutathione Transferase -- metabolism
- Humans
- Intestine, Small -- metabolism
- Liver -- metabolism
- Male
- Models, Biological
- Mutagens -- toxicity
- Rats, Sprague-Dawley
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Publication Type: Journal Article
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