Compound mutations in BCR-ABL1 are not major drivers of primary or secondary resistance to ponatinib in CP-CML patients. [electronic resource]
Producer: 20160629Description: 703-12 p. digitalISSN:- 1528-0020
- Amino Acid Substitution
- Chemotherapy, Adjuvant
- DNA Mutational Analysis -- methods
- Drug Resistance, Neoplasm -- genetics
- Fusion Proteins, bcr-abl -- genetics
- High-Throughput Nucleotide Sequencing
- Humans
- Imidazoles -- therapeutic use
- Leukemia, Myeloid, Chronic-Phase -- drug therapy
- Mutation -- physiology
- Neoadjuvant Therapy
- Protein Kinase Inhibitors -- therapeutic use
- Pyridazines -- therapeutic use
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Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
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