Identification of novel autophagic Radix Polygalae fraction by cell membrane chromatography and UHPLC-(Q)TOF-MS for degradation of neurodegenerative disease proteins. [electronic resource]
Producer: 20160919Description: 17199 p. digitalISSN:- 2045-2322
- Animals
- Autophagy -- drug effects
- Cell Membrane -- chemistry
- Chromatography, High Pressure Liquid
- Drugs, Chinese Herbal -- isolation & purification
- Huntingtin Protein
- Inhibitory Concentration 50
- Mice, Knockout
- Nerve Tissue Proteins -- metabolism
- Neurodegenerative Diseases -- drug therapy
- Nuclear Proteins -- metabolism
- PC12 Cells
- Polygala -- chemistry
- Proteolysis
- Rats
- Saponins -- isolation & purification
- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
- Triterpenes -- isolation & purification
- alpha-Synuclein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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