Novel Etoposide Analogue Modulates Expression of Angiogenesis Associated microRNAs and Regulates Cell Proliferation by Targeting STAT3 in Breast Cancer. [electronic resource]
Producer: 20160706Description: e0142006 p. digitalISSN:- 1932-6203
- Apoptosis -- drug effects
- Breast Neoplasms -- drug therapy
- Caspase 9 -- metabolism
- Cell Cycle Checkpoints -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- DNA Damage -- drug effects
- Enzyme Activation -- drug effects
- Etoposide -- analogs & derivatives
- Gene Expression Regulation, Neoplastic
- Human Umbilical Vein Endothelial Cells -- drug effects
- Humans
- MCF-7 Cells
- MicroRNAs -- biosynthesis
- Models, Molecular
- Molecular Docking Simulation
- Neovascularization, Pathologic -- pathology
- Podophyllotoxin -- analogs & derivatives
- Protein Binding
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Quinazolines -- pharmacology
- RNA Interference
- RNA, Small Interfering -- genetics
- STAT3 Transcription Factor -- metabolism
- Vascular Endothelial Growth Factor A -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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