Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance. [electronic resource]
Producer: 20160609Description: 1645-56 p. digitalISSN:- 1097-0215
- Adult
- Alternative Splicing
- Antineoplastic Agents -- therapeutic use
- Blotting, Western
- Child
- Drug Resistance, Neoplasm -- physiology
- Female
- Flow Cytometry
- Humans
- Male
- Methotrexate -- therapeutic use
- Peptide Synthases -- metabolism
- Precursor Cell Lymphoblastic Leukemia-Lymphoma -- drug therapy
- Real-Time Polymerase Chain Reaction
- Reverse Transcriptase Polymerase Chain Reaction
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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