Dimeric bis (heptyl)-Cognitin Blocks Alzheimer's β-Amyloid Neurotoxicity Via the Inhibition of Aβ Fibrils Formation and Disaggregation of Preformed Fibrils. [electronic resource]
Producer: 20161018Description: 953-61 p. digitalISSN:- 1755-5949
- Alzheimer Disease -- drug therapy
- Amyloid -- drug effects
- Amyloid beta-Peptides -- toxicity
- Animals
- Cell Line, Tumor
- Cell Survival -- drug effects
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Drug Evaluation, Preclinical
- Humans
- Male
- Maze Learning -- drug effects
- Memory Disorders -- drug therapy
- Neuroprotective Agents -- chemistry
- Peptide Fragments -- toxicity
- Rats, Sprague-Dawley
- Reactive Oxygen Species -- metabolism
- Tacrine -- analogs & derivatives
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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