Assessment of ixekizumab, an interleukin-17A monoclonal antibody, for potential effects on reproduction and development, including immune system function, in cynomolgus monkeys. [electronic resource]
Producer: 20160926Description: 160-73 p. digitalISSN:- 1873-1708
- Age Factors
- Animals
- Antibodies, Monoclonal, Humanized -- toxicity
- Biomarkers -- blood
- Embryonic Development -- drug effects
- Female
- Fertility -- drug effects
- Fetal Development -- drug effects
- Fetus -- drug effects
- Gestational Age
- Immune System -- drug effects
- Immunologic Factors -- toxicity
- Macaca fascicularis
- Male
- Pregnancy
- Prenatal Exposure Delayed Effects
- Reproduction -- drug effects
- Risk Assessment
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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