Efficient Fludarabine-Activating PNP From Archaea as a Guidance for Redesign the Active Site of E. Coli PNP. [electronic resource]
Producer: 20161213Description: 1126-35 p. digitalISSN:- 1097-4644
- Adenosine -- chemistry
- Arabinonucleosides -- chemistry
- Archaeal Proteins -- chemistry
- Binding, Competitive
- Biocatalysis
- Catalytic Domain
- Crystallography, X-Ray
- Escherichia coli Proteins -- chemistry
- Isoenzymes -- chemistry
- Kinetics
- Models, Molecular
- Molecular Structure
- Protein Binding
- Protein Domains
- Purine-Nucleoside Phosphorylase -- chemistry
- Substrate Specificity
- Sulfolobus solfataricus -- enzymology
- Vidarabine -- analogs & derivatives
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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