A bacterial metabolite induces glutathione-tractable proteostatic damage, proteasomal disturbances, and PINK1-dependent autophagy in C. elegans. [electronic resource]
Producer: 20160621Description: e1908 p. digitalISSN:- 2041-4889
- Animals
- Autophagy
- Bacterial Toxins -- toxicity
- Caenorhabditis elegans -- drug effects
- Caenorhabditis elegans Proteins -- physiology
- Glutathione -- metabolism
- Homeostasis
- Mitochondria -- physiology
- Neurodegenerative Diseases -- microbiology
- Neurons -- physiology
- Proteasome Endopeptidase Complex -- metabolism
- Protein Serine-Threonine Kinases -- physiology
- Proteostasis Deficiencies -- microbiology
- Streptomyces -- chemistry
- alpha-Synuclein -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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