Induction of Broad-Based Immunity and Protective Efficacy by Self-amplifying mRNA Vaccines Encoding Influenza Virus Hemagglutinin. [electronic resource]
Producer: 20160426Description: 332-44 p. digitalISSN:- 1098-5514
- Animals
- Antibodies, Neutralizing -- blood
- Antibodies, Viral -- blood
- CD4-Positive T-Lymphocytes -- immunology
- CD8-Positive T-Lymphocytes -- immunology
- Cross Protection
- Disease Models, Animal
- Female
- Ferrets
- Hemagglutinin Glycoproteins, Influenza Virus -- genetics
- Influenza Vaccines -- administration & dosage
- Leukocyte Reduction Procedures
- Mice, Inbred BALB C
- Orthomyxoviridae Infections -- immunology
- RNA, Messenger -- genetics
- Respiratory System -- virology
- Survival Analysis
- Treatment Outcome
- Vaccines, DNA -- administration & dosage
- Viral Load
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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