Combination of zoledronic acid and serine/threonine phosphatase inhibitors induces synergistic cytotoxicity and apoptosis in human breast cancer cells via inhibition of PI3K/Akt pathway. [electronic resource]
Producer: 20170213Description: 3665-73 p. digitalISSN:- 1423-0380
- Apoptosis -- drug effects
- Blotting, Western
- Breast Neoplasms -- metabolism
- Cell Line, Tumor
- Cell Survival -- drug effects
- Diphosphonates -- pharmacology
- Dose-Response Relationship, Drug
- Drug Synergism
- Enzyme Inhibitors -- pharmacology
- Female
- Humans
- Imidazoles -- pharmacology
- MCF-7 Cells
- Marine Toxins
- Okadaic Acid -- pharmacology
- Oxazoles -- pharmacology
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphoprotein Phosphatases -- antagonists & inhibitors
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction -- drug effects
- Zoledronic Acid
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Publication Type: Journal Article
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