Mitochondrial ATF2 translocation contributes to apoptosis induction and BRAF inhibitor resistance in melanoma through the interaction of Bim with VDAC1. [electronic resource]
Producer: 20161026Description: 36338-53 p. digitalISSN:- 1949-2553
- Animals
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- metabolism
- Bcl-2-Like Protein 11
- Cell Line, Tumor
- Humans
- Melanoma -- drug therapy
- Melanoma, Experimental -- drug therapy
- Membrane Proteins -- metabolism
- Mice
- Mitochondria -- metabolism
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins B-raf -- antagonists & inhibitors
- Transfection
- Voltage-Dependent Anion Channel 1 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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