Efficient gene-targeting in rat embryonic stem cells by CRISPR/Cas and generation of human kynurenine aminotransferase II (KAT II) knock-in rat. [electronic resource]
Producer: 20160823Description: 991-1001 p. digitalISSN:- 1573-9368
- Animals
- Base Sequence
- Blotting, Southern
- CRISPR-Cas Systems
- Cells, Cultured
- Embryonic Stem Cells -- cytology
- Female
- Gene Targeting
- Homologous Recombination
- Humans
- Kynurenic Acid -- metabolism
- Male
- Molecular Sequence Data
- RNA, Messenger -- genetics
- Rats
- Rats, Long-Evans
- Rats, Wistar
- Real-Time Polymerase Chain Reaction
- Reverse Transcriptase Polymerase Chain Reaction
- Sequence Homology, Nucleic Acid
- Transaminases -- genetics
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Publication Type: Journal Article
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