MDM2 Inhibitor, Nutlin 3a, Induces p53 Dependent Autophagy in Acute Leukemia by AMP Kinase Activation. [electronic resource]
Producer: 20160606Description: e0139254 p. digitalISSN:- 1932-6203
- Adenylate Kinase -- metabolism
- Autophagy -- drug effects
- Blotting, Western
- Cell Line, Tumor
- Enzyme Activation -- drug effects
- Flow Cytometry
- Humans
- Imidazoles -- pharmacology
- Lentivirus -- genetics
- Leukemia -- metabolism
- Microscopy, Confocal
- Microscopy, Electron, Transmission
- Piperazines -- pharmacology
- Proto-Oncogene Proteins c-mdm2 -- antagonists & inhibitors
- Tumor Suppressor Protein p53 -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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