Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts. [electronic resource]
Producer: 20160812Description: 34561-72 p. digitalISSN:- 1949-2553
- Animals
- Antineoplastic Agents -- pharmacology
- Cell Line, Tumor
- Colorectal Neoplasms -- genetics
- Drug Resistance, Neoplasm -- genetics
- Humans
- Immunoblotting
- MAP Kinase Kinase Kinases -- antagonists & inhibitors
- Mice
- Oligonucleotide Array Sequence Analysis
- Pyridones -- pharmacology
- Pyrimidinones -- pharmacology
- Transcriptome
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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