The lincRNA HOTAIRM1, located in the HOXA genomic region, is expressed in acute myeloid leukemia, impacts prognosis in patients in the intermediate-risk cytogenetic category, and is associated with a distinctive microRNA signature. [electronic resource]
Producer: 20160808Description: 31613-27 p. digitalISSN:- 1949-2553
- Adolescent
- Adult
- Aged
- Biomarkers, Tumor -- genetics
- Chi-Square Distribution
- Cytogenetic Analysis
- Disease Progression
- Disease-Free Survival
- Female
- Gene Expression Profiling -- methods
- Gene Expression Regulation, Neoplastic
- Genetic Predisposition to Disease
- Homeodomain Proteins -- genetics
- Humans
- Kaplan-Meier Estimate
- Leukemia, Myeloid, Acute -- genetics
- Male
- MicroRNAs -- genetics
- Middle Aged
- Multivariate Analysis
- Mutation
- Nuclear Proteins -- genetics
- Nucleophosmin
- Odds Ratio
- Phenotype
- Predictive Value of Tests
- Proportional Hazards Models
- RNA, Long Noncoding -- genetics
- Risk Assessment
- Risk Factors
- Time Factors
- Treatment Outcome
- Young Adult
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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