Maternal diabetes triggers DNA damage and DNA damage response in neurulation stage embryos through oxidative stress. [electronic resource]
Producer: 20160201Description: 407-12 p. digitalISSN:- 1090-2104
- Animals
- Cell Line
- Checkpoint Kinase 1
- Checkpoint Kinase 2 -- genetics
- Crosses, Genetic
- Cyclic N-Oxides -- pharmacology
- DNA Damage
- Diabetes, Gestational -- chemically induced
- Embryo, Mammalian
- Female
- Gene Expression Regulation
- Glucose -- antagonists & inhibitors
- Histones -- genetics
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Neural Stem Cells -- drug effects
- Neurulation -- genetics
- Oxidative Stress
- Phosphorylation
- Pregnancy
- Protein Kinases -- genetics
- Signal Transduction
- Spin Labels
- Streptozocin
- Superoxide Dismutase -- deficiency
- Superoxide Dismutase-1
- Tumor Suppressor Protein p53 -- genetics
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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