Alternative to LRRK2-IN-1 for Pharmacological Studies of Parkinson's Disease. [electronic resource]
Producer: 20160916Description: 240-7 p. digitalISSN:- 1423-0313
- Animals
- Benzodiazepinones -- adverse effects
- Blood-Brain Barrier -- drug effects
- Caco-2 Cells
- Cell Survival -- drug effects
- Drug Discovery -- methods
- Drug Stability
- Hep G2 Cells
- Hepatocytes -- drug effects
- Humans
- Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
- Male
- Metabolic Clearance Rate
- Microsomes, Liver -- drug effects
- Parkinson Disease -- drug therapy
- Protein Kinase Inhibitors -- adverse effects
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Pyrimidines -- adverse effects
- Rats, Sprague-Dawley
- Substrate Specificity
- Tissue Distribution
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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