Elucidating the Role of Residue 67 in IMP-Type Metallo-β-Lactamase Evolution. [electronic resource]
Producer: 20160831Description: 7299-307 p. digitalISSN:- 1098-6596
- Amino Acid Substitution
- Catalytic Domain
- Escherichia coli -- enzymology
- Evolution, Molecular
- Gene Expression
- Hydrolysis
- Kinetics
- Microbial Sensitivity Tests
- Molecular Docking Simulation
- Mutation
- Phenylalanine -- chemistry
- Protein Structure, Secondary
- Recombinant Proteins -- chemistry
- Structure-Activity Relationship
- Substrate Specificity
- Valine -- chemistry
- beta-Lactamases -- chemistry
- beta-Lactams -- chemistry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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