BET inhibitor resistance emerges from leukaemia stem cells. [electronic resource]
Producer: 20151019Description: 538-42 p. digitalISSN:- 1476-4687
- Animals
- Azepines -- pharmacology
- Benzodiazepines -- pharmacology
- Cell Cycle Proteins
- Cell Line, Tumor
- Cells, Cultured
- Chromatin -- metabolism
- Clone Cells -- drug effects
- Drug Resistance, Neoplasm -- drug effects
- Epigenesis, Genetic
- Gene Expression Regulation, Neoplastic -- drug effects
- Genes, myc -- genetics
- Hematopoietic Stem Cells -- cytology
- Humans
- Leukemia, Myeloid, Acute -- drug therapy
- Mice
- Molecular Targeted Therapy
- Neoplastic Stem Cells -- drug effects
- Nuclear Proteins -- antagonists & inhibitors
- Transcription Factors -- antagonists & inhibitors
- Transcription, Genetic -- drug effects
- Triazoles -- pharmacology
- Wnt Signaling Pathway -- drug effects
- beta Catenin -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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