Modification of paclitaxel-loaded solid lipid nanoparticles with 2-hydroxypropyl-β-cyclodextrin enhances absorption and reduces nephrotoxicity associated with intravenous injection. [electronic resource]
Producer: 20160831Description: 5397-405 p. digitalISSN:- 1178-2013
- 2-Hydroxypropyl-beta-cyclodextrin
- Albumins -- chemistry
- Animals
- Antineoplastic Agents -- chemistry
- Apoptosis
- Area Under Curve
- Breast Neoplasms
- Cell Proliferation
- Cell Survival
- Creatinine -- blood
- Drug Carriers -- pharmacokinetics
- Drug Screening Assays, Antitumor
- Female
- Flow Cytometry
- Humans
- Injections, Intravenous
- Kidney -- drug effects
- Lipids -- chemistry
- MCF-7 Cells
- Male
- Mice
- Mice, Inbred BALB C
- Microscopy, Confocal
- Nanoparticles -- chemistry
- Neoplasm Transplantation
- Paclitaxel -- chemistry
- Rats
- beta-Cyclodextrins -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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