Kinase-independent role for CRAF-driving tumour radioresistance via CHK2. [electronic resource]
Producer: 20160420Description: 8154 p. digitalISSN:- 2041-1723
- Animals
- Cell Line, Tumor
- Checkpoint Kinase 2 -- metabolism
- DNA Damage -- genetics
- Fluorescent Antibody Technique
- HCT116 Cells
- Humans
- Immunoblotting
- Immunoprecipitation
- Mice
- Mutation
- Neoplasm Transplantation
- Phosphorylation -- radiation effects
- Proto-Oncogene Proteins B-raf -- genetics
- Proto-Oncogene Proteins c-raf -- genetics
- Radiation Tolerance -- genetics
- Radiation, Ionizing
- Serine -- metabolism
- Xenograft Model Antitumor Assays
- p21-Activated Kinases -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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