The PTTG1-targeting miRNAs miR-329, miR-300, miR-381, and miR-655 inhibit pituitary tumor cell tumorigenesis and are involved in a p53/PTTG1 regulation feedback loop. [electronic resource]
Producer: 20160811Description: 29413-27 p. digitalISSN:- 1949-2553
- 3' Untranslated Regions
- Animals
- Apoptosis
- Binding Sites
- Carcinogenesis -- genetics
- Cell Line, Tumor
- Cell Movement
- Cell Proliferation
- Cell Survival
- Feedback, Physiological
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Mice, Nude
- MicroRNAs -- genetics
- Neoplasm Invasiveness
- Pituitary Neoplasms -- genetics
- Securin -- genetics
- Signal Transduction
- Time Factors
- Transcription, Genetic
- Transfection
- Tumor Suppressor Protein p53 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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