The sum of gains and losses of genes encoding the protein tyrosine kinase targets predicts response to multi-kinase inhibitor treatment: Characterization, validation, and prognostic value. [electronic resource]
Producer: 20160722Description: 26388-99 p. digitalISSN:- 1949-2553
- Adult
- Aged
- Algorithms
- Antineoplastic Agents -- therapeutic use
- Biomarkers, Tumor -- antagonists & inhibitors
- DNA Copy Number Variations
- Decision Support Techniques
- Disease-Free Survival
- Female
- Gene Amplification
- Gene Deletion
- Gene Expression Profiling
- Genetic Testing -- methods
- Humans
- Kaplan-Meier Estimate
- Male
- Middle Aged
- Molecular Targeted Therapy
- Neoplasms -- drug therapy
- Patient Selection
- Precision Medicine
- Predictive Value of Tests
- Protein Kinase Inhibitors -- therapeutic use
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Reproducibility of Results
- Risk Factors
- Signal Transduction
- Time Factors
- Treatment Outcome
- Young Adult
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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